Is it factual that book reviewers will not review a self published book? Or that some bookstores won't carry them at all?
Once upon a time, there was a huge prejudice against self-published books. The idea was that if they were good enough, a publisher would pick them up. If no publisher wanted them, then they weren't very good.
While there are still a multitude of examples of books that support that prejudice, there are also many self-published books that are absolutely wonderful—but that just couldn't find a good fit with a traditional publisher.
If you self-publish, you generally are going to have a harder row to hoe when it comes to getting attention and shelf space. Self-published fiction is very difficult to get into bookstores; non-fiction is a little easier. If you're planning to go this route, I strongly recommend you do your research, starting with these books:
The Complete Guide to Self-Publishing
Dan Poynter's Self-Publishing Manual
Jump Start Your Book Sales
Guerrilla Marketing for Writers
I'd also suggest you talk to some people who have successfully self-published and get their input.
And have your distribution avenues set up BEFORE you spend a lot of money designing and printing your book.
So to answer your question: Some reviewers will not review self-published books, some will. Some bookstores will not carry self-published books, some will.