Go read Is This a Query You Sent Me? at Thoughts from a Literary Agent by Marisa Iozzi Corvisiero.
And lest you think the query she posted is a one-time, unusual occurrence, let me assure you it is not. I get queries and submissions similar to this ALL. THE. TIME.
And yes, in my day job, I usually e-mail back something like, "Thank you for your submission. Unfortunately, at this time it is not a good match for our company. Good luck in your search for publication."